Why Lyme disease is common in the northern US, but rare in the south: The roles of host choice, host-seeking behavior, and tick density

by Howard S. Ginsberg, Graham J. Hickling, Russell L. Burke, Nicholas H. Ogden, Lorenza Beati, Roger A. LeBrun, Isis M. Arsnoe, Richard Gerhold, Seungeun Han, Kaetlyn Jackson, Lauren Maestas, Teresa Moody, Genevieve Pang, Breann Ross, Eric L. Rulison, Jean I. Tsao Lyme disease is common in the northeastern United States, but rare in the southeast, even though the tick vector is found in both regions. Infection prevalence of Lyme spirochetes in host-seeking ticks, an important component to the risk of Lyme disease, is also high in the northeast and northern midwest, but declines sharply in the south. As ticks must acquire Lyme spirochetes from infected vertebrate hosts, the role of wildlife species composition on Lyme disease risk has been a topic of lively academic discussion. We compared tick–vertebrate host interactions using standardized sampling methods among 8 sites scattered throughout the eastern US. Geographical trends in diversity of tick hosts are gradual and do not match the sharp decline in prevalence at southern sites, but tick–host associations show a clear shift from mammals in the north to reptiles in the south. Tick infectio n prevalence declines north to south largely because of high tick infestation of efficient spirochete reservoir hosts (rodents and shrews) in the north but not in the south. Minimal infestation of small mammals in the south results from strong selective attachment to lizards such as skinks (which ar e inefficient reservoirs f...
Source: PLoS Biology: Archived Table of Contents - Category: Biology Authors: Source Type: research

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A 37-year-old man was diagnosed with Lyme carditis after presenting to the emergency department (ED) with fever, weakness, history of tick bite, and prolonged PR interval of 394 ms (a type of heart block) and positive Lyme testing. In the ED, second-degree AV block was noted intermittently on the monitor but not documented. Both infectiousRead more …Why I’m furious over observation status originally appeared inKevinMD.com.
Source: Kevin, M.D. - Medical Weblog - Category: General Medicine Authors: Tags: Conditions Hospital-Based Medicine Source Type: blogs
Source: Journal of Neurology - Category: Neurology Source Type: research
ConclusionsBorrelia infection in the setting of acute aortic pathology is a rare entity. To our knowledge, this is the first case report to demonstrate a mycotic abdominal aortic aneurysm as a rare manifestation of Lyme disease. Aortic wall biopsies and real-time polymerase chain reaction analysis of the specimen were essential for accurate diagnosis. This finding may contribute to the understanding of the etiology of inflammatory aneurysmal disease and abdominal aneurysms in general.
Source: Journal of Medical Case Reports - Category: General Medicine Source Type: research
A number of tick-borne pathogens circulate in the Belgian tick population in addition to the causative agent of Lyme borreliosis. However, so far, only a few patients with tick-borne diseases other than Lyme b...
Source: Parasites and Vectors - Category: Microbiology Authors: Tags: Research Source Type: research
Source: International Journal of Infectious Diseases - Category: Infectious Diseases Authors: Source Type: research
CONCLUSIONS: Clinical and topical variants and forms of EF in children are associated with etiology, have different rates of complications, the nature of the course and outcomes, the knowledge of which makes it possible to optimize the diagnostic process.PMID:35038852 | DOI:10.17116/jnevro202112111286
Source: Herpes - Category: Infectious Diseases Authors: Source Type: research
Vaccine. 2022 Jan 13:S0264-410X(22)00006-8. doi: 10.1016/j.vaccine.2022.01.003. Online ahead of print.ABSTRACTVaccination guidelines for dogs and cats indicate that core vaccines (for dogs, rabies, distemper, adenovirus, parvovirus; for cats, feline parvovirus, herpes virus-1, calicivirus) are essential to maintain health, and that non-core vaccines be administered according to a clinician's assessment of a pet's risk of exposure and susceptibility to infection. A reliance on individual risk assessment introduces the potential for between-practice inconsistencies in non-core vaccine recommendations. A study was initiated t...
Source: Herpes - Category: Infectious Diseases Authors: Source Type: research
Conclusion: This systematic review, including all reported cases and our case report, supports evidence of ocular infection ofBorrelia species. Furthermore, in case of suspicion of infection and seronegativity, it is justified to look forBorrelia in eye tissue samples. In addition, microscopy without using PCR is not sufficient to confirm the diagnosis of borreliosis on ocular tissue. In the articles studied, there was no unambiguous recommendation of treatment.Ophthalmic Res
Source: Ophthalmic Research - Category: Opthalmology Source Type: research
Psychol Med. 2022 Jan 11:1-2. doi: 10.1017/S0033291721005481. Online ahead of print.ABSTRACTAfter reading an article in the journal, regarding affective disorders in patients with rare illnesses, the authors would like to discuss a case of non-affective psychosis, presenting with olfactory reference and Truman symptoms, in a patient with three unusual conditions: Gilbert disease, Hughes syndrome and Lyme neuroborreliosis.PMID:35012695 | DOI:10.1017/S0033291721005481
Source: Psychological Medicine - Category: Psychiatry Authors: Source Type: research
Neurol Sci. 2022 Jan 10. doi: 10.1007/s10072-022-05865-8. Online ahead of print.ABSTRACTA 35-year-old Caucasian woman presented an abrupt onset of bilateral impaired vision, and arrived to our attention two weeks later. She had a previous episode of mild dizziness. She underwent a fluorescein angiography showing branch retinal artery occlusions and a brain magnetic resonance imaging (MRI) revealing several supraand infratentorial FLAIR-hyperintense white matter lesions, two with contrast enhancement. Thrombophilic, autoimmune and infective (including Human Immunodeficiency Virus, Borrelia burgdorferi, Hepatitis B Virus, He...
Source: Herpes - Category: Infectious Diseases Authors: Source Type: research
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