Ex vivo potential of a quinoline-derivative nail lacquer as a new alternative for dermatophytic onychomycosis treatment.

Conclusion. Treatment with the quinoline-derivative lacquer showed a significant inhibitory effect on T. rubrum strain in this infection model. Finally, the compound presents high potential for application in a formulation such as nail lacquer as a possible treatment for dermatophytic onychomycosis.
PMID: 33502306 [PubMed - as supplied by publisher]

Source: Journal of Medical Microbiology - January 27, 2021 Category: Microbiology Authors: Machado GDRM, Pippi B, Berlitz S, Diedrich D, Defferrari D, Lopes W, Gnoatto SCB, Kulkamp-Guerreiro IC, Vainstein MH, Jean M, Van de Weghe P, de Andrade SF, Fuentefria AM Tags: J Med Microbiol Source Type: research