Increased oxytocin release precedes hyponatremia after pituitary surgery

ConclusionTaken together, these results show for the first time that urinary OXT output remains normally stable after transsphenoidal pituitary surgery. OXT excretion however becomes abnormally high on or around 4 days after surgery in patients later developing hyponatremia, suggesting that this abnormal dynamics of OXT secretion might serve as an early marker for transsphenoidal surgery-related hyponatremia attributed to SIADH.

http://link.springer.com/10.1007/s11102-020-01121-4

Source: Pituitary - January 28, 2021 Category: Endocrinology Source Type: research