RSF1 requires CEBP/ β and hSNF2H to promote IL-1β-mediated angiogenesis: the clinical and therapeutic relevance of RSF1 overexpression and amplification in myxofibrosarcomas

In conclusion, RSF1 overexpression, partly attributable toRSF1 amplification, contributes a novel proangiogenic function by partnering with CEBP/ β to cotransactivateIL1B, highlighting its prognostic, pathogenetic, and therapeutic relevance in myxofibrosarcomas.
Source: Angiogenesis - Category: Molecular Biology Source Type: research