Bioreactor Development for Lung Tissue Engineering

Conclusions Significant advances in bioreactors for lung engineering have been made at both the microfluidic and the macroscale. The most advanced are closed systems that incorporate pressure-controlled perfusion and ventilation and are amenable to automation. Ex vivo lung perfusion systems have advanced to clinical trials for lung preservation and reconditioning. The biggest challenges that lie ahead for lung bioengineering can only be overcome by future advances in technology that solve the problems of cell production and tissue incorporation.
Source: Current Transplantation Reports - Category: Transplant Surgery Source Type: research