Procoagulant activity in high grade serous ovarian cancer patients following neoadjuvant chemotherapy-the role of the activated protein c pathway

Ovarian cancer patients are at high risk of thrombosis particularly during chemotherapy treatment however the mechanism is not understood. The aim of this study is to investigate the role of the activated protein C (APC) pathway in the procoagulant activity observed in ovarian cancer patients undergoing neoadjuvant chemotherapy.

Source: Thrombosis Research - January 25, 2021 Category: Hematology Authors: Mark P. Ward, Feras Abu Saadeh, Sharon A. O ’Toole, John J. O’Leary, Noreen Gleeson, Lucy A. Norris Source Type: research