Nascent fusion pore opening monitored at single-SNAREpin resolution [Biophysics and Computational Biology]

Vesicle fusion with a target membrane is a key event in cellular trafficking and ensures cargo transport within the cell and between cells. The formation of a protein complex, called SNAREpin, provides the energy necessary for the fusion process. In a three-dimensional microfluidic chip, we monitored the fusion of small...

Source: Proceedings of the National Academy of Sciences - January 25, 2021 Category: Science Authors: Paul Heo, Jeff Coleman, Jean-Baptiste Fleury, James E. Rothman, Frederic Pincet Tags: Biological Sciences Source Type: research