Mechanistic basis of propofol-induced disruption of kinesin processivity [Biophysics and Computational Biology]
Propofol is a widely used general anesthetic to induce and maintain anesthesia, and its effects are thought to occur through impact on the ligand-gated channels including the GABAA receptor. Propofol also interacts with a large number of proteins including molecular motors and inhibits kinesin processivity, resulting in significant decrease in...
Source: Proceedings of the National Academy of Sciences - Category: Science Authors: Mandira Dutta, Susan P. Gilbert, Jose N. Onuchic, Biman Jana Tags: Biophysics and Computational Biology Physical Sciences Source Type: research
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