Mechanistic basis of propofol-induced disruption of kinesin processivity [Biophysics and Computational Biology]

Propofol is a widely used general anesthetic to induce and maintain anesthesia, and its effects are thought to occur through impact on the ligand-gated channels including the GABAA receptor. Propofol also interacts with a large number of proteins including molecular motors and inhibits kinesin processivity, resulting in significant decrease in...
Source: Proceedings of the National Academy of Sciences - Category: Science Authors: Tags: Biophysics and Computational Biology Physical Sciences Source Type: research