Medications for Pregnant Women With Obesity: Special Considerations

Pregnant women with obesity are at increased risk of a multitude of complications of pregnancy and adverse perinatal outcomes. The risk of some of these complications, such as neural tube defects or preeclampsia, may be mitigated by some medications. Other complications, such as diabetes, venous thromboembolism, and infections, require treatment with medications. Given the changes in pharmacokinetics and pharmacodynamics during pregnancy, which is further enhanced by obesity, the optimal medication and its dose is often researched. This chapter further explores the different complications and common medications that women with obesity are likely to require.
Source: Clinical Obstetrics and Gynecology - Category: OBGYN Tags: Diabesity: Type 2 Diabetes and Obesity Source Type: research

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Conclusion: The incidence of penile and anal high-grade intraepithelial neoplasia and SCC in men with diabetes was increased compared with men without diabetes. For penile and anal SCCs, this was primarily due to an increased risk in men with T2D.
Source: Epidemiology - Category: Epidemiology Tags: Infectious Diseases Source Type: research
Conclusion: Among individuals with obesity, the weight-loss group had a lower risk of coronary heart disease but not of stroke. Weight gain was associated with increased risk of CVD across BMI groups. See video abstract at,
Source: Epidemiology - Category: Epidemiology Tags: Chronic Diseases Source Type: research
No abstract available
Source: Epidemiology - Category: Epidemiology Tags: Letters Source Type: research
New UCLA-led research indicates that simple text messages emphasizing the easy availability of COVID-19 vaccines successfully boosted the number of people who got the shot.The researchers, from theDavid Geffen School of Medicine at UCLA, theUCLA Anderson School of Management and Carnegie Mellon University, say their findings held true across all demographics, including groups that have been hesitant to receive the vaccine.“We found that text messages that stressed the accessibility of the vaccine and that included ‘ownership’ language — such as ‘The vaccine has just been made available for you...
Source: UCLA Newsroom: Health Sciences - Category: Universities & Medical Training Source Type: news
This study aims to assess the influence of hepatic steatosis on iron deficiency and replacement therapy after bariatric surgery.MethodsSeventy-nine individuals undergoing gastric bypass have been studied at 4 time points (preoperative and 1, 3, and 6  months after surgery). Weight, body mass index (BMI), iron, ferritin, vitamin B12, folate, hemoglobin, gamma-glutamyl transferase (GGT), alanine aminotransferase (ALT), aspartate aminotransferase (AST), and use of iron replacement were recorded.ResultsForty-two individuals (53%) had moderate/severe steatosis assessed by ultrasound. No differences were seen in iron profil...
Source: Obesity Surgery - Category: Surgery Source Type: research
This study aimed to evaluate its ecology and to identify this Legionella species as a respiratory pathogen. A PCR assay for detecting the L. feeleii mip gene was developed to identify it in clinical and environmental samples. Culture and PCR were performed in environmental samples from four drinking water treatment plants (DWTPs). Free L. feeleii was only detected in raw water samples (3.4%), while L. feeleii as an Acanthamoeba endosymbiont was found in 30.7% of raw water, 11.5% of decanter biofilm, and 32% of finished water samples. Therefore, Acanthamoeba spp. plays an essential role in the multiplication, persistence, a...
Source: Frontiers in Microbiology - Category: Microbiology Source Type: research
Studies have shown that a low-carb (less than 130g a day), higher-protein diet can actually be beneficial for people with type 2 diabetes. It could even reverse their condition as one study suggested.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
CONSISTENTLY high blood sugar will lead to disastrous health complications, including diabetic nephropathy - the deterioration of the kidneys. This condition is said to affect 40 percent of those with type 2 diabetes.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
This article expresses sentiments regarding medical technology and human longevity that we'd all like to see more of in the mainstream media. At some point, it will come to be seen by the average person as basically sensible to work towards minimizing the tide of suffering and death caused aging and age-related disease. It has been, in hindsight, a strange thing to live in a world in which most people were reflexively opposed to that goal. Death and aging constitute a mystery. Some of us die more quickly. We often ask about it as children, deny it in youth, and reluctantly come to accept it as adults. Aging is uni...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
Giuseppe Ristagno1*, Francesca Fumagalli1, Barbara Bottazzi2, Alberto Mantovani2,3,4, Davide Olivari1, Deborah Novelli1 and Roberto Latini1 1Department of Cardiovascular Research, Mario Negri Institute for Pharmacological Research IRCCS, Milan, Italy 2Humanitas Clinical and Research Center-IRCCS, Milan, Italy 3Humanitas University, Milan, Italy 4The William Harvey Research Institute, Queen Mary University of London, London, United Kingdom The long pentraxin PTX3 is a member of the pentraxin family produced locally by stromal and myeloid cells in response to proinflammatory signals and microbial moieties. The p...
Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research
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