The Microbiota-Gut-Brain Axis: From Motility to Mood

The gut-brain axis plays an important role in maintaining homeostasis. Many intrinsic and extrinsic factors influence signaling along this axis, modulating the function of both the enteric and central nervous systems. More recently the role of the microbiome as an important factor in modulating gut-brain signaling has emerged and the concept of a microbiota-gut-brain axis has been established. In this review, we highlight the role of this axis in modulating enteric and central nervous system function and how this may impact disorders such as Irritable Bowel Syndrome and disorders of mood and affect.
Source: Gastroenterology - Category: Gastroenterology Authors: Source Type: research