Characterization of crystalline forms of gaxilose, a diagnostic drug.

Characterization of crystalline forms of gaxilose, a diagnostic drug. Carbohydr Res. 2021 Jan 08;499:108232 Authors: Catti F, Gallego SH, Benito M, Molins E, Olóndriz FM Abstract Lactose intolerance is a pathology caused by lactase enzyme deficiency, usually produced in the intestinal cells provoking symptoms as abdominal pain, bloating, diarrhea, gas and nausea. Gaxilose, 4-O-β-D galactopyranosyl-d-xylose, is used as a diagnostic drug for a non-invasive method for hypolactasia diagnosis. To date, no definitive guide for identifying gaxilose and distinguishing between crystalline forms is available. Data have been collected from a number of different analytical techniques in order to provide a full characterization of the compound and a simple method to discriminate between two solid forms. PMID: 33472139 [PubMed - as supplied by publisher]
Source: Carbohydrate Research - Category: Genetics & Stem Cells Authors: Tags: Carbohydr Res Source Type: research