Stress-induced resistance to fear memory destabilization is associated with an impairment of Lys-48-linked protein polyubiquitination in the Basolateral Amygdala: influence of D-cycloserine.
In conclusion, the protein polyubiquitination-dependent destabilization is impaired after the recall of stress-induced resistant memories, with D-cycloserine restoring such molecular event. Hence, the present report contributes to furthercharacterize the neurobiological events associated with stress-induced memory resistance as well as to corroborate the connection between glutamatergic signaling,protein degradation and memory destabilization in stress-induced resistant memories.
PMID: 33476748 [PubMed - as supplied by publisher]
Source: Neurobiology of Learning and Memory - Category: Neurology Authors: Javier Espejo P, Ortiz V, Delia Martijena I, Alejandro Molina V Tags: Neurobiol Learn Mem Source Type: research