Can we diagnose concussion easily?

Concussion is generally defined as a traumatic, impulsive force transmitted to the head that results in rapid onset of transiently impaired neurological function. This straightforward definition does not result, however, in an easily reproducible diagnosis of concussion, as prior studies in The Journal (J Pediatr 2015;166;1214-20) have shown. A number of proprietary tests have been deployed for diagnosis, yet those all have limitations in regard to sensitivity, reliability, and expense.
Source: The Journal of Pediatrics - Category: Pediatrics Authors: Tags: The Editors' Perspectives Source Type: research

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The Sports Concussion Assessment Tool (SCAT) is a pen and paper-based evaluation tool for use by healthcare professionals in the acute evaluation of suspected concussion. Here we present a feasibility study towards instrumented SCAT (iSCAT). Traditionally,...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news
Condition:   Concussion, Mild Intervention:   Sponsors:   Milton S. Hershey Medical Center;   National Institutes of Health (NIH) Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
The objective of this stu...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news
Condition:   Concussion, Mild Intervention:   Sponsors:   Milton S. Hershey Medical Center;   National Institutes of Health (NIH) Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
CONCLUSIONS: Developmental and sociological factors were differentially associated with concussion-related knowledge, attitudes, and self-reporting intentions. These results can inform medical providers, parents, and coaches with regard to context-specific clinical assessments of concussion symptoms. PMID: 33032324 [PubMed - as supplied by publisher]
Source: Journal of Athletic Training - Category: Sports Medicine Tags: J Athl Train Source Type: research
PURPOSE: To screen the entire genome for genetic markers associated with risk for concussion. METHODS: A genome-wide-association (GWA) analyses was performed utilizing data from the Kaiser Permanente Research Board (KPRB) and the United Kingdom (UK) Bi...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Research Methods, Surveillance and Codes, Models Source Type: news
Closed-head, frontal impacts in which the brain undergoes both lateral and rotational acceleration comprise the majority of human traumatic brain injury (TBI). Here, we utilize a clinically relevant model to examine the effects of a single concussion on aspects of brain integrity: the blood–brain barrier, the perineuronal nets (PNNs), and diffuse axonal injury. Adult, male Sprague–Dawley rats received either a frontal, closed-head concussive TBI, or no injury and were evaluated at 1- or 7-day post-injury. Using immunolabeling for albumin, we observed a significant increase in the permeability of the blood&ndash...
Source: NeuroReport - Category: Neurology Tags: Degeneration and Repair Source Type: research
We report the study protocol of a pilot study funded under the South-Central Mental Illness Research, Education, and Clinical Center pilot study program from the U.S. Department of Veterans Affairs. This randomized, open-label study was designed to evaluate the feasibility of completing a randomized trial of quetiapine vs. treatment as usual to promote patient engagement in PTSD patients with a history of mTBI.DiscussionWe expect that the success of this ongoing study should provide us with the preliminary data necessary to design a full-scale randomized trial. Positive efficacy results in a full- scale trial should inform...
Source: Military Medical Research - Category: International Medicine & Public Health Source Type: research
Conditions:   Mild Traumatic Brain Injury;   Concussion, Mild Intervention:   Device: Graded Exercise Therapy: ClearPlay(TM) Sponsor:   ANSwers Neuroscience, Inc. Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
OBJECTIVE: To investigate the use of the King-Devick (K-D) test for sideline assessment of concussive injuries in a New Zealand amateur women's rugby union team. DESIGN: Prospective cohort observational. METHODS: All players were K-D tested during ...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Recreational and Sports Issues Source Type: news
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