Identification of a small molecule as inducer of ferroptosis and apoptosis through ubiquitination of GPX4 in triple  negative breast cancer cells

TNBC is the most aggressive breast cancer with higher recurrence and mortality rate than other types of breast cancer. There is an urgent need for identification of therapeutic agents with unique mode of actio...

Source: Journal of Hematology and Oncology - January 20, 2021 Category: Hematology Authors: Yahui Ding, Xiaoping Chen, Can Liu, Weizhi Ge, Qin Wang, Xin Hao, Mengmeng Wang, Yue Chen and Quan Zhang Tags: Research Source Type: research