BRCA1 and BRCA2 mutations in ovarian cancer patients from Belarus: update

ConclusionsThe frequency of 13 causativeBRCA1 andBRCA2 founder mutations in West Belarus was higher than in other Slavic countries. Testing ofBRCA1 (c.5266dupC, c.4035delA, c.3756_3759delGTCT, c.68_69delAG, c.1687C > T as well as c.181 T > G) andBRCA2 (c.658_659delGT) mutations should be considered an inexpensive and sensitive test panel for this population.

http://link.springer.com/10.1186/s13053-021-00169-y

Source: Hereditary Cancer in Clinical Practice - January 21, 2021 Category: Cancer & Oncology Source Type: research