Synergy of entry inhibitors with direct-acting antivirals uncovers novel combinations for prevention and treatment of hepatitis C

Conclusions
Our results provide a rationale for the development of antiviral strategies combining entry inhibitors with DAAs or HTAs by taking advantage of synergy. The uncovered combinations provide perspectives for efficient strategies to prevent liver graft infection and novel interferon-free regimens.

Source: Gut - February 3, 2015 Category: Gastroenterology Authors: Xiao, F., Fofana, I., Thumann, C., Mailly, L., Alles, R., Robinet, E., Meyer, N., Schaeffer, M., Habersetzer, F., Doffoel, M., Leyssen, P., Neyts, J., Zeisel, M. B., Baumert, T. F. Tags: Open access Hepatology Source Type: research