Nonintervention Is Not Noninferior to Oral Ibuprofen for Treatment of Patent Ductus Arteriosus

To the Editor This Letter highlights the flaws of a recent randomized clinical trial by Sung et al that concluded that nonintervention is noninferior to oral ibuprofen for patent ductus arteriosus (PDA) treatment in reducing death or bronchopulmonary dysplasia (BPD) in preterm infants.
Source: JAMA Pediatrics - Category: Pediatrics Source Type: research