New study identifies opposite roles of sugars and fat on cellular immunotherapy of cancer

(Instituto de Medicina Molecular) The team led by Bruno Silva Santos, Principal Investigator iMM, discovered that the functions of a subtype of white blood cells - gamma delta T cells - are regulated by metabolic resources, namely sugars and fat. The results now published in the scientific journal Nature Immunology, open new avenues for the use of sugar metabolism in gamma-delta T cells as an effective tool in cellular immunotherapy of cancer, in addition to building further on the concept that high cholesterol levels are a barrier to its effectiveness.
Source: EurekAlert! - Cancer - Category: Cancer & Oncology Source Type: news