Circulating chemerin levels are determined through circulating platelet counts in nondiabetic Taiwanese people: A bidirectional Mendelian randomization study

Platelet count (PLT) is a predictor of metabolic and inflammation-related disorders. Platelets can release prochemerin, which acts as a link between coagulation and inflammation and between innate and adaptive immunity. The causal effect between PLT and circulating chemerin level has not been elucidated. Methods: Nondiabetic participants with samples in the Taiwan Biobank were recruited for genome-wide association study (GWAS) based on PLT (17,037 participants) and chemerin level (3887 participants).
Source: Atherosclerosis - Category: Cardiology Authors: Source Type: research