The effect of Four Approaches to treat Actinic Keratosis on the Health Related Quality of Life, as assessed by the Skindex-29 and AKQoL

To evaluate the impact of actinic keratosis (AK) and the effect of four AK treatments on the health-related quality of life (HRQoL), the Skindex-29 and AKQoL questionnaires were completed by 624 patients with AK participating in a randomized controlled trial (RCT) comparing 5% fluorouracil-cream, 5% imiquimod-cream, methyl-aminolevulinate photodynamic therapy (MAL-PDT), and 0.015% ingenol mebutate gel.(Jansen et al., 2019) In this trial, the probability of treatment success at 12 months was 74.7% for fluorouracil, 53.9% for imiquimod, 37.7% for MAL-PDT, and 28.9% for ingenol mebuate.

Source: Journal of Investigative Dermatology - January 17, 2021 Category: Dermatology Authors: Shima Ahmady, Maud H.E. Jansen, Patty J. Nelemans, Brigitte A.B. Essers, Janneke P.H.M. Kessels, Nicole W.J. Kelleners-Smeets, Klara Mosterd Tags: Letters to the Editor Source Type: research