Viruses, Vol. 13, Pages 123: Update on the Transmission of Zika Virus Through Breast Milk and Breastfeeding: A Systematic Review of the Evidence

Viruses, Vol. 13, Pages 123: Update on the Transmission of Zika Virus Through Breast Milk and Breastfeeding: A Systematic Review of the Evidence Viruses doi: 10.3390/v13010123 Authors: Elizabeth Centeno-Tablante Melisa Medina-Rivera Julia L. Finkelstein Heather S. Herman Pura Rayco-Solon Maria Nieves Garcia-Casal Lisa Rogers Kate Ghezzi-Kopel Mildred P. Zambrano Leal Joyce K. Andrade Velasquez Juan G. Chang Asinc Juan Pablo Peña-Rosas Saurabh Mehta We systematically searched regional and international databases and screened 1658 non-duplicate records describing women with suspected or confirmed ZIKV infection, intending to breastfeed or give breast milk to an infant to examine the potential of mother-to-child transmission of Zika virus (ZIKV) through breast milk or breastfeeding-related practices. Fourteen studies met our inclusion criteria and inform this analysis. These studies reported on 97 mother–children pairs who provided breast milk for ZIKV assessment. Seventeen breast milk samples from different women were found positive for ZIKV via RT-PCR, and ZIKV replication was found in cell cultures from five out of seven breast milk samples from different women. Only three out of six infants who had ZIKV infection were breastfed, no evidence of clinical complications was found to be associated with ZIKV RNA in breast milk. This review updates our previous report by including 12 new articles, in which we found no evidence of ZIKV ...
Source: Viruses - Category: Virology Authors: Tags: Review Source Type: research