Narrative review of the novel coronavirus SARS-CoV-2: update on genomic characteristics, transmissions and animal model.

Narrative review of the novel coronavirus SARS-CoV-2: update on genomic characteristics, transmissions and animal model. J Thorac Dis. 2020 Dec;12(12):7454-7466 Authors: Zhang Z, Zhang L, Zhu A, Wang Y, Guan W, Zeng Z, Sun J, Li F, Zhao J, Yang Z, Zhao J, Zhong N Abstract Two outbreaks of severe respiratory infection caused by severe acute respiratory syndrome coronavirus (SARS-CoV) and the Middle East respiratory syndrome coronavirus (MERS-CoV) caused global pandemics and highlighted the importance of preparedness for respiratory CoVs. Recently, a third highly pathogenic CoV, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), was first identified in Wuhan, Hubei, China and posed a public health crisis worldwide. Here, we focus on the recent advances of the novel CoV, and discuss its genomic similarity with other CoVs, transmission, animal model and clinical treatment of coronavirus disease 2019 (COVID-19) induced by SARS-CoV-2, which help epidemic prevention and control, and guide treatment strategies. PMID: 33447433 [PubMed]
Source: Journal of Thoracic Disease - Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research