Transient Receptor Potential Vanilloid 4 channel participates in mouse ventricular electrical activity.
CONCLUSION: This study shows for the first time that TRPV4 modulates AP and QTc durations and constitutes thereby a good therapeutical target against long QT-mediated ventricular arrhythmias.
PMID: 33449852 [PubMed - as supplied by publisher]
Source: American Journal of Physiology. Heart and Circulatory Physiology - Category: Physiology Authors: Chaigne S, Cardouat G, Louradour J, Vaillant F, Charron S, Sacher F, Ducret T, Guinamard R, Vigmond E, Hof T Tags: Am J Physiol Heart Circ Physiol Source Type: research