Diagnosis of Dry Eye Disease Using Principal Component Analysis: A Study in Animal Models of the Disease.

CONCLUSIONS: PCA proved useful for evaluating DED providing a simpler, more comprehensive assessment than ICTP. PC 1 is a valuable, clinically relevant, and informative metric for DED status and severity having superior diagnostic value and statistical strength compared to ICTP. Spatial information on biplots of PC 1 vs PC 3 is also informative. PCA, and specifically PC 1, has the potential to serve as a biomarker for DED.
PMID: 33445973 [PubMed - as supplied by publisher]

Source: Current Eye Research - January 14, 2021 Category: Opthalmology Authors: Honkanen R, Nemesure B, Huang L, Rigas B Tags: Curr Eye Res Source Type: research