Alterations in Cerebral Hemodynamics During Microgravity: A Literature Review.

Alterations in Cerebral Hemodynamics During Microgravity: A Literature Review. Med Sci Monit. 2021 Jan 15;27:e928108 Authors: Du J, Cui J, Yang J, Wang P, Zhang L, Luo B, Han B Abstract Most reported neurological symptoms that happen after exposure to microgravity could be originated from alterations in cerebral hemodynamics. The complicated mechanisms involved in the process of hemodynamics and the disparate experimental protocols designed to study the process may have contributed to the discrepancies in results between studies and the lack of consensus among researchers. This literature review examines spaceflight and ground-based studies of cerebral hemodynamics and aims to summarize the underlying physiological mechanisms that are altered in cerebral hemodynamics during microgravity. We reviewed studies that were published before July 2020 and sought to provide a comprehensive summary of the physiological or pathological theories of hemodynamics and to arrive at firm conclusions from incongruous results that were reported in those related articles. We give plausible explanations of inconsistent results on factors including intracranial pressure, cerebral blood flow, and cerebrovascular autoregulation. Although there are no definitive data to confirm how cerebral hemodynamics changes during microgravity, every discrepancy in results was interpreted by existing theories, which were derived from physiological and pathological proces...
Source: Medical Science Monitor - Category: Research Tags: Med Sci Monit Source Type: research