Test of robustness of pharyngeal neural networks in Caenorhabditis elegans

The nematode worm Caenorhabditis elegans is a model for deciphering the neural circuitry that transmits information from sensory organ to muscle tissue. It is also studied for disentangling the characteristics of the network, the efficiency of its design, and for testing theoretical models on how information is encoded. For this study, the efficiency of the synaptic connections was studied by testing the robustness of the neural network. A randomization test of robustness was applied to previously computed neural modules of the pharynx of C. elegans. The results support robustness as a reason for the observed over connectiveness across the pharyngeal system. In addition, rare events of single-neuron loss may expectedly lead to loss of function in a neural system.

Source: NeuroReport - January 13, 2021 Category: Neurology Tags: Cellular, Molecular and Developmental Neuroscience Source Type: research