Dantrolene induces mitigation of myocardial ischemia-reperfusion injury by ryanodine receptor inhibition

The objective of the present study was to evaluate the in-vivo impact of dantrolene sodium on myocardial ischemia-reperfusion injury in swine models. An in vivo, experimental trial comparing 10 experimental animals which received dantrolene sodium with 9 control swine models was conducted.

Source: Seminars in Thoracic and Cardiovascular Surgery - January 15, 2021 Category: Cardiovascular & Thoracic Surgery Authors: Ilias Samiotis, Nikolaos A. Papakonstantinou, Panagiotis Dedeilias, Ioannis Vasileiadis, Apostolos Papalois, Spyridon Deftereos, Anastasia Kotanidou Tags: ADULT – Original Submission Source Type: research