Conventional Ultrafiltration - No More Role in Elective Adult Cardiac Surgery?

Introduction of the cardiopulmonary bypass (CPB) machine by John Gibbon in 1952 has revolutionized the field of cardiac surgery by allowing complex open-heart procedures to be performed in a bloodless surgical field and is widely regarded as one of the most significant surgical developments in the 20th century.1 However, the use of CPB is not without its disadvantages. Its non-physiological nature has been shown to trigger a systemic inflammatory response syndrome (SIRS) contributing to the development of multi-organ dysfunction particularly the heart, lungs, kidneys, central nervous and coagulation systems.
Source: Journal of Cardiothoracic and Vascular Anesthesia - Category: Anesthesiology Authors: Tags: Editorial Source Type: research