Malaria in the USA: How Vulnerable Are We to Future Outbreaks?

This article aims to reviewAnopheles mosquito data, vector-borne disease outbreak preparedness, and human travel data from large international gateway cities in an effort to examine risk for localized outbreaks.Recent FindingsThe majority of vector control organizations are widely unprepared for a vector-borne disease outbreak, and multiple mosquito species capable of transmitting malaria continue to persist throughout the USA.SummaryDespite the lack of recent autochthonous cases in the USA, multiple risk factors suggest that local malaria outbreaks in the USA will continue to pose a public health threat due to large numbers of international travelers from endemic areas, multipleAnopheles spp. capable of transmitting the parasite, and unsatisfactory vector-borne disease outbreak preparedness. Climate conditions and recent changes in travel patterns will influence malaria across the globe.
Source: Current Tropical Medicine Reports - Category: Tropical Medicine Source Type: research

Related Links:

ConclusionFindings from the current study indicate low-level exposure to the chikungunya virus suggesting the virus is circulating and potentially causing morbidity in Ghana.
Source: PLoS Neglected Tropical Diseases - Category: Tropical Medicine Authors: Source Type: research
Acta Trop. 2021 Jul 9:106040. doi: 10.1016/j.actatropica.2021.106040. Online ahead of print.ABSTRACTIndia is a malaria endemic country which is targeting malaria elimination by 2027. Transmission intensities are low-to-moderate depending on the region supported by multiple disease vectors. Among these, comparatively North-East India contributes to high proportions of malaria cases annually, the majority of which are due to Plasmodium falciparum (90%). Anopheles minimus and An. baimaii (sibling species in the An. dirus complex) are widely prevalent and incriminated as vectors of malaria. Number of intervention tools were fi...
Source: Acta Tropica - Category: Infectious Diseases Authors: Source Type: research
A once in a century new viral outbreak, COVID-19, has caused unfathomable numbers of deaths, toward 4 million. Yet an ancient disease, malaria, endemic to the residents of more than half of Earth, is even more devastating than this pandemic over time: It caused about 12 million deaths in the...
Source: Proceedings of the National Academy of Sciences - Category: Science Authors: Tags: Biochemistry, Commentaries Commentary Source Type: research
This study aims to evaluate the mutations in four P. vivax drug resistance markers pvcrt-o (putative), pvmdr1 (putative), pvdhfr and pvdhps in 44 isolates from Malaysia. Finding indicates that 27.3%, 100%, 47.7%, and 27.3% of the isolates were carrying mutant allele in pvcrt-o, pvmdr1, pvdhfr and pvdhps genes, respectively. Most of the mutant isolates had multiple point mutations rather than single point mutation in pvmdr1 (41/44) and pvdhfr (19/21). One novel point mutation V111I was detected in pvdhfr. Allelic combination analysis shows significant strong association between mutations in pvcrt-o and pvmdr1 (X2 = 9.521, P
Source: Acta Tropica - Category: Infectious Diseases Authors: Tags: Acta Trop Source Type: research
by Ernest Diez Benavente, Monica Campos, Jody Phelan, Debbie Nolder, Jamille G. Dombrowski, Claudio R. F. Marinho, Kanlaya Sriprawat, Aimee R. Taylor, James Watson, Cally Roper, Francois Nosten, Colin J. Sutherland, Susana Campino, Taane G. Clark AlthoughPlasmodium vivax parasites are the predominant cause of malaria outside of sub-Saharan Africa, they not always prioritised by elimination programmes.P.vivax is resilient and poses challenges through its ability to re-emerge from dormancy in the human liver. With observed growing drug-resistance and the increasing reports of life-threatening infections, new tools to inform...
Source: PLoS Genetics - Category: Genetics & Stem Cells Authors: Source Type: research
Climate change is the greatest health challenge of the 21st century, and threatens all aspects of society, says the WHO in its COP24 Special Report. What could digital health technologies do to support the fight against the climate crisis? How could healthcare processes, facilities, medical devices become more sustainable? As it is humanity’s priority to mitigate the worsening as well as the impact of rising temperatures and extreme weather events, we tried to figure out what role digital health could assume here. We found many options – and even more possibilities for future development. The climate crisis...
Source: The Medical Futurist - Category: Information Technology Authors: Tags: Future of Medicine air asthma climate climate catastrophe climate change climate crisis digital digital health efficient Healthcare mosquito optimize resilience solar sustainability technology Source Type: blogs
This report summarizes confirmed malaria cases in persons with onset of illness in 2016 and summarizes trends in previous years. DESCRIPTION OF SYSTEM: Malaria cases diagnosed by blood film microscopy, polymerase chain reaction, or rapid diagnostic tests are reported to local and state health departments by health care providers or laboratory staff members. Case investigations are conducted by local and state health departments, and reports are transmitted to CDC through the National Malaria Surveillance System (NMSS), the National Notifiable Diseases Surveillance System (NNDSS), or direct CDC consultations. CDC refer...
Source: MMWR Surveill Summ - Category: Epidemiology Authors: Tags: MMWR Surveill Summ Source Type: research
The objective of the study was to estimate the malaria incidence attributable to the 2013 flood in Almanagil Locality, Gezira State in central Sudan. Methods Study Area Gezira State is located in the east-central region of Sudan, is crossed by the Blue Nile and is irrigated by two canals of the Gezira and Managil agriculture schemes. Almanagil Locality was in 2013 one of the 8 localities that constituted the Gezira State and was situated in the south western part of the state. Almanagil Town, the capital of the locality, is 62 km away from Wadmedani, the capital of Gezira State, and 156 km from Khartoum, the capital o...
Source: PLOS Currents Disasters - Category: International Medicine & Public Health Authors: Source Type: research
LITFL • Life in the Fast Lane Medical Blog LITFL • Life in the Fast Lane Medical Blog - Emergency medicine and critical care medical education blog aka Tropical Travel Trouble 010 Peer Reviewer: Dr Jennifer Ho, ID physician QLD, Australia You are an ED doc working in Perth over schoolies week. An 18 yo man comes into ED complaining of fever, rash a “cracking headache” and body aches. He has just hopped off the plane from Bali where he spent the last 2 weeks partying, boozing and running amok. He got bitten by “loads” of mosquitoes because he forgot to take insect repellent. On e...
Source: Life in the Fast Lane - Category: Emergency Medicine Authors: Tags: Clinical Cases Tropical Medicine arthralgia dengue fever rash Source Type: blogs
We described a time series of malaria incidence for the 72 months of study for the entire area and divided by state. To address irregularities and error components, we smoothed the time series using a centred moving average of k=5, in which k is the number of observations that are averaged. This value was selected because it highlighted the best pattern of the data. We used the method of seasonal decomposition by Loess smoothing to capture the trend, seasonal and irregular components. A generalized linear model was applied to quantify this overall trend, and the Kruskal-Wallis Rank Sum test was applied to test for seasonal...
Source: PLOS Currents Outbreaks - Category: Epidemiology Authors: Source Type: research
More News: Endemics | International Medicine & Public Health | Malaria | Outbreaks | Parasitic Diseases | Parasitology | Tropical Medicine