Kratom Alkaloids, Natural and Semi-Synthetic, Show Less Physical Dependence and Ameliorate Opioid Withdrawal.

In conclusion, while retaining some liabilities, kratom, mitragynine, and mitragynine pseudoindoxyl produced significantly less physical dependence and ameliorated precipitated withdrawal in morphine-dependent animals, suggesting some clinical value. PMID: 33433723 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/33433723?dopt=Abstract

Source: Cellular and Molecular Neurobiology - January 12, 2021 Category: Cytology Authors: Wilson LL, Chakraborty S, Eans SO, Cirino TJ, Stacy HM, Simons CA, Uprety R, Majumdar S, McLaughlin JP Tags: Cell Mol Neurobiol Source Type: research