Phagocytosis: Sweet Repulsions via the Glycocalyx.

Phagocytosis: Sweet Repulsions via the Glycocalyx.
Curr Biol. 2021 Jan 11;31(1):R20-R22
Authors: Maschalidi S, Ravichandran KS
Abstract
New work shows that the glycocalyx meshwork on the surface of macrophages prevents phagocytic receptors from binding their ligands by two means - electrostatic charge and steric hindrance. Components of this barrier are present on pathogenic and malignant targets that elude phagocytosis.
PMID: 33434480 [PubMed - in process]

Source: Current Biology - January 11, 2021 Category: Biology Authors: Maschalidi S, Ravichandran KS Tags: Curr Biol Source Type: research