Saffloflavone, a new flavonoid from the flowers of Carthamus tinctorius L. and its cardioprotective activity.

Saffloflavone, a new flavonoid from the flowers of Carthamus tinctorius L. and its cardioprotective activity.
Nat Prod Res. 2021 Jan 12;:1-6
Authors: Wang MN, Cao YG, Wei YX, Ren YJ, Liu YL, Chen X, He C, Zheng XK, Feng WS
Abstract
A new flavonoid, saffloflavone , along with six known compounds, kaempferol-3-O-rutinoside, kaempferol-3-O-sophoroside, quercetin-3-O-β-d-glucoside, quercetin-7-O-β-d-glucoside, luteolin-7-O-β-d-glucoside and kaempferol 3-O-β-d-glucoside were isolated from the flowers of Carthamus tinctorius L. All the structures were determined by interpretation of their spectroscopic data. The cardioprotective effects of all the isolates against oxidative stress of H9c2 cells induced by H2O2 were investigated. The results showed that compounds 4-6 exhibited protective effects against of H9c2 cells injury induced by H2O2.
PMID: 33432825 [PubMed - as supplied by publisher]

Source: Natural Product Research - January 12, 2021 Category: Biochemistry Authors: Wang MN, Cao YG, Wei YX, Ren YJ, Liu YL, Chen X, He C, Zheng XK, Feng WS Tags: Nat Prod Res Source Type: research