Cytokines in the colon, central nervous system and serum of irritable bowel syndrome rats

ConclusionFrom the research, it can be inferred that IL-1 β may participate in the pathogenesis mechanism of IBS via regulating the colon function. The increasing expression of CRF linked to stress in the spinal cord, hypothalamus and the third ventricle indicated that it might play an important role in the mechanisms of visceral hypersensitivity signal c onduction pathway.
Source: European Journal of Medical Research - Category: Research Source Type: research