A Para-Bombay Blood Group Case Associated with a Novel < b > < i > FUT1 < /i > < /b > Mutation c.361G & #x3e;A

Conclusions: A novelFUT1 allele (FUT1*c.361G#x3e;A) was identi fied in a Chinese individual with para-Bombay B phenotype. TheFUT1c.361G#x3e;A mutation may significantly downregulate the expression of H antigens on RBCs by damaging the enzyme conformation.Transfus Med Hemother
Source: Transfusion Medicine and Hemotherapy - Category: Hematology Source Type: research