IgM pemphigoid

How does this article integrate into what was already known? Cases of predominant or exclusive linear IgM deposition at the DEJ in pemphigoid diseases have been described. The relevance of IgM in pathophysiology of pemphigoid is under debate. How does it change practice? That is, what does the article mean to the practice of dermatology and what should you do as a result of having read this article? What should change in the way you practice? Detection of IgM autoantibodies targeting Col17 may constitute to a previously underrecognized phenotype, highlighting the role of IgM in AIBD.

Source: Journal of the American Academy of Dermatology - January 12, 2021 Category: Dermatology Authors: Katharina Boch, Christoph M. Hammers, Stephanie Goletz, Mayumi Kamaguchi, Ralf J. Ludwig, Stefan W. Schneider, Detlef Zillikens, Eva Hadaschik, Enno Schmidt Source Type: research