Further assessment of Salvia haenkei as an innovative strategy to counteract skin photo-aging and restore the barrier integrity.

In this study, SH extract was tested on human keratinocyte cell line (HaCaT) exposed to stress factors related to premature aging of cells such as free radicals and ultraviolet B radiation. We confirmed that SH acts as scavenger of ROS and found its ability to restore the skin barrier integrity by reinforcing the cytoskeleton structure, sealing the tight junctions and increasing the migration rate of cells. Given these results, this work becomes relevant, identifying Salvia haenkei as a compound useful for anti-aging skin treatment in clinical performance.
PMID: 33424011 [PubMed - as supplied by publisher]

Source: Aging - January 8, 2021 Category: Biomedical Science Authors: Cocetta V, Cadau J, Saponaro M, Giacomini I, Dall'Acqua S, Sut S, Catanzaro D, Orso G, Miolo G, Menilli L, Pagetta A, Ragazzi E, Montopoli M Tags: Aging (Albany NY) Source Type: research