Effect of patient immunodeficiencies on the diagnostic performance of serological assays to detect Aspergillus-specific antibodies in chronic pulmonary aspergillosis
Prevalence of chronic pulmonary aspergillosis (CPA) is ∼3 million patients worldwide, and detection of Aspergillus-specific antibody is a critical diagnostic component. Some patients with CPA have subtle immune deficits possibly contributing to poor Aspergillus antibody production and false negative results.
Source: Respiratory Medicine - Category: Respiratory Medicine Authors: Elizabeth Stucky Hunter, Bayu Wilopo, Malcolm D. Richardson, Chris Kosmidis, David W. Denning Source Type: research