Peripheral and Pulmonary Effects of Inorganic ‐Nitrite during Exercise in Heart Failure with Preserved Ejection Fraction

ConclusionSodium nitrite enhances skeletal muscle O2 conductance during exercise as well as pulmonary O2 diffusion, optimizing O2 kinetics in tandem with increased convective O2 delivery through cardiac output augmentation. The favorable combined pulmonary, cardiac and peripheral effects of nitrite may improve exercise tolerance in people with HFpEF and requires further investigation.
Source: European Journal of Heart Failure - Category: Cardiology Authors: Tags: Research Article Source Type: research