A randomized-controlled trial comparing liposomal bupivacaine, plain bupivacaine, and the mixture of liposomal bupivacaine and plain bupivacaine in transversus abdominus plane block for postoperative analgesia for open abdominal hysterectomies

ConclusionsIn this small study at risk of being under-powered, the mixture of liposomal bupivacaine with plain bupivacaine for TAP block did not improve analgesia compared with either liposomal bupivacaine or plain bupivacaine on their own.Trial registrationwww.clinicaltrials.gov (NCT03250507); registered 5 April 2017.

http://link.springer.com/10.1007/s12630-020-01911-1

Source: Canadian Journal of Anesthesia - January 11, 2021 Category: Anesthesiology Source Type: research