Increased particle size of triacylglycerol-enriched remnant lipoproteins, but not their plasma concentration or lipid content, augments risk prediction of incident type 2 diabetes

Conclusions/interpretationTRL particle diameter improves the prediction of diabetes, but only in individuals with HbA1c<39  mmol/mol (5.7%) at baseline. These data support TRL particle diameter as a risk factor that is changed early in the course of the pathophysiological processes that lead to the development of type 2 diabetes, even before glucose abnormalities are established.Graphical abstract
Source: Diabetologia - Category: Endocrinology Source Type: research