Late post ‐natal neurometabolic development in healthy male rats using 1H and 31P Magnetic Resonance Spectroscopy

In conclusion, the present study showed important changes in brain metabolites in both the hippocampus and cerebellum in the later post ‐natal period (p29/p35‐p77) of male rats, something previously unreported. Based on these novel data, changes in some neurometabolites beyond p28‐35, conventionally accepted as the cut off for adulthood, should be taken into account in both experimental design and data interpretation in this a nimal model.

Source: Journal of Neurochemistry - January 9, 2021 Category: Neuroscience Authors: Veronika Ra čkayová, Dunja Simicic, Guillaume Donati, Olivier Braissant, Rolf Gruetter, Valérie A. McLin, Cristina Cudalbu Tags: ORIGINAL ARTICLE Source Type: research