Tipping the Scale: MYC Gains Weight in Fanconi Anemia Bone Marrow Failure Progression.

Tipping the Scale: MYC Gains Weight in Fanconi Anemia Bone Marrow Failure Progression. Cell Stem Cell. 2021 Jan 07;28(1):8-9 Authors: Renaudin X, Rosselli F Abstract Fanconi anemia (FA) is an inherited syndrome of bone marrow failure (BMF) due to disrupted DNA repair. In this issue of Cell Stem Cell, Rodríguez et al. (2021) show that blood stem cells from FA patients have abnormal and inflammation-induced MYC expression, which promotes their proliferation in the face of increasing DNA damage. PMID: 33417873 [PubMed - as supplied by publisher]
Source: Cell Stem Cell - Category: Stem Cells Authors: Tags: Cell Stem Cell Source Type: research