Engagement of TREM2 by a novel monoclonal antibody induces activation of microglia and improves cognitive function in Alzheimer ’s disease models

Genetic variants and mutations in triggering receptor expressed in myeloid cells (TREM2) are associated with premature and late onset Alzheimer ’s disease (AD).

Source: Journal of Neuroinflammation - January 9, 2021 Category: Neurology Authors: Michael Fassler, Maya Saban Rappaport, Clara Benaim Cu ño and Jacob George Tags: Research Source Type: research