Biomarkers for Bladder Pain Syndrome/Interstitial Cystitis

AbstractPurpose of ReviewIn this manuscript, the literature published in the past 5  years about BPS/IC biomarkers was reviewed. Topics include BPS/IC biomarkers, the classical BPS/IC diagnostic, clinical outcomes as a new concept of BPS/IC phenotyping biomarkers, BPS/IC urinary biomarkers, BPS/IC bladder tissue biomarkers and BPS/IC biomarkers outside the bladder.Recent FindingsThe importance of patients ’ phenotyping and sub-grouping emerged as a way of finding new BPS/IC biomarkers and treatment. Also, the use of non-invasive methodologies and of artificial intelligence approaches has been gaining momentum in BPS/IC biomarkers studies.SummaryBiomarker research points to the need of following an approach based on a systemic theory instead of a bladder-centred theory. Also, the importance of sample size and the choice of controls to validate BPS/IC biomarkers have been elevated.
Source: Current Bladder Dysfunction Reports - Category: Urology & Nephrology Source Type: research