The Unfolded Protein Response in the Human Infant Brain and Dysregulation Seen in Sudden Infant Death Syndrome (SIDS)

This study indicates that subgroups of SIDS infants, defined by risk exposure, had activation of the UPR in several nuclei relating to p roprioception and motor control, suggesting that the UPR underlies the neuroreceptor system changes responsible for these physiological functions, leading to compromise in the pathogenesis of SIDS.
Source: Molecular Neurobiology - Category: Neurology Source Type: research