Phosphine modification of proline-glycine-proline tripeptide and study of its neuroprotective properties.

CONCLUSION: Preliminary biological tests have shown that the obtained phosphine analog of the proline-glycine-proline tripeptide is involved in modulating the formation of sediments in the cellular system of proteinopathy, which may indicate their potential antiaggregatory properties.
PMID: 33412416 [PubMed - as supplied by publisher]

Source: Biochemical and Biophysical Research communications - January 4, 2021 Category: Biochemistry Authors: Alexey VV, Maxim DE, Lyudmila AA, Alexey UA, Valery SP, Kristina SN, Boris LV, Vladimir FM, Yuriy DA, Valery RV, Nikolay MF Tags: Biochem Biophys Res Commun Source Type: research