Evaluating Health Risks from Inhaled Polychlorinated Biphenyls: Research Needs for Addressing Uncertainty

Conclusions: In certain contexts, inhalation exposure to PCBs may contribute more to total PCB exposure than previously assumed. New epidemiological and toxicological studies addressing the potential health impacts of inhaled PCBs may be useful for quantifying exposure–response relationships and evaluating risks. Citation: Lehmann GM, Christensen K, Maddaloni M, Phillips LJ. 2015. Evaluating health risks from inhaled polychlorinated biphenyls: research needs for addressing uncertainty. Environ Health Perspect 123:109–113; http://dx.doi.org/10.1289/ehp.1408564 Address correspondence to G.M. Lehmann, U.S. EPA, MD B243-01, 4930 Old Page Rd., Durham, NC 27703 USA. Telephone: 919-541-2289. E-mail: lehmann.geniece@epa.gov We are grateful to K. Thomas, G. Woodall, L. Burgoon, R. Sams, J. Vandenberg, K. Deener, L. Flowers, and D. Walsh (U.S. EPA) for providing a thorough review of the draft manuscript. The views expressed in this article are those of the authors and do not necessarily reflect the views or policies of the U.S. EPA. The authors declare they have no actual or potential competing financial interests. Received: 15 April 2014 Accepted: 7 October 2014 Advance Publication: 10 October 2014 Final Publication: 1 February 2015 Supplemental Material (298 KB) PDF Introduction Polychlorinated biphenyls (PCBs) consist of two linked benzene rings in which one or more of the hydrogen atoms have been replaced by chlorine atoms. Te...
Source: EHP Research - Category: Environmental Health Authors: Tags: Commentary February 2015 Source Type: research