In vitro and in vivo evaluation of [ 125/123 I]-2-[4-(2-iodophenyl)piperidino]cyclopentanol([ 125/123 I]-OI5V) as a potential sigma-1 receptor ligand for SPECT

ConclusionsThis study confirmed that [125/123I]OI5V selectively binds σ-1R in the rat brain in vivo. [123I]OI5V was suggested to be useful as a σ-1R ligand for SPECT.

http://link.springer.com/10.1007/s12149-020-01552-w

Source: Annals of Nuclear Medicine - January 8, 2021 Category: Nuclear Medicine Source Type: research