Analysis of gamma-glutamyltransferase in acute promyelocytic leukemia patients undergoing arsenic trioxide treatment.

CONCLUSION: Single elevation in GGT without elevated aminotransferases can't be identified as hepatotoxicity, and the elevated levels of GGT are associated with increasing leukocyte counts. Continue single-agent ATO without prophylactic hepatoprotective agents is recommended in APL patients with single elevation in GGT, in order to maintain ATO effect. PMID: 33402059 [PubMed - in process]

https://www.ncbi.nlm.nih.gov/pubmed/33402059?dopt=Abstract

Source: Hematology - January 8, 2021 Category: Hematology Tags: Hematology Source Type: research