Persistence of both reversible airway obstruction and higher blood eosinophils may predict lung function decline in severe asthma

ConclusionPersistent SABA ‐induced FEV1>12%, especially when associated to BE>300 cells/mL, may be a marker of accelerated lung function decline in severe asthmatics despite maximal step ‐5 treatment. The highest bronchodilation associated to the lowest BE levels should be the main goal of asthma treatment to prevent such decline.

Source: The Clinical Respiratory Journal - January 5, 2021 Category: Respiratory Medicine Authors: Bruno Sposato, Marco Scalese, Alberto Ricci, Paola Rogliani, Pierluigi Paggiaro, The Omalizumab Italian Study Group Tags: BRIEF REPORT Source Type: research